TRanscranial AlterNating current Stimulation FOR patients with Mild Alzheimer's Disease (TRANSFORM-AD study): Protocol for a randomized controlled clinical trial.

Yi Xing,Penghu Wei,Changming Wang,Yi Shan, Yueying Yu,Yuchen Qiao,Beijia Xie,Xinrui Shi, Zhongfang Zhu,Jie Lu,Guoguang Zhao,Jianping Jia,Yi Tang

Alzheimer's & dementia (New York, N. Y.)（2020）

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摘要

This trial will evaluate the efficacy and safety of 40 Hz tACS in patients with AD, and further explore the potential mechanisms by analyzing amyloid deposits using PiB-PET, brain volume and white matter integrity by structural MRI, and neural activity by EEG and EEG-fMRI.

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关键词

Alzheimer's disease,gamma frequency,randomized controlled clinical trial,transcranial alternating current stimulation

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