Gasdermins deliver a deadly punch to cancer
CELL RESEARCH(2020)
摘要
The pore-forming gasdermin proteins mediate a lytic and pro-inflammatory form of cell death called pyroptosis and have been linked to the host defense against infection. Two recent studies published in Nature revealed that induction of pyroptosis in tumor cells promotes anti-tumor activity, highlighting gasdermins as potential new targets in cancer immunotherapy.
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关键词
Innate immunity,Tumour immunology,Life Sciences,general,Cell Biology
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