Photodynamic inactivation of methicillin-resistant Staphylococcus aureus on skin using a porphyrinic formulation

Photodiagnosis and Photodynamic Therapy(2020)

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摘要
•MRSA is a multidrug-resistant pathogen involved on skin and soft tissue infections.•The effect of a porphyrinic formulation (FORM) to photoinactivate MRSA was assessed.•FORM, without coadjutants, is a promising approach for MRSA inactivation on skin.•Potassium iodide (KI) and iodopovidone (PVP-I) were used as potentiators of FORM.•In vitro KI and PVP-I addition to FORM resulted in potentiation but not on skin.
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关键词
Antimicrobial photodynamic therapy,Porphyrinic formulation,Potentiator agents,Potassium iodide,Iodopovidone,Methicillin-resistant Staphylococcus aureus
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