Risk of major bleeding associated with aspirin use in non-surgical critically ill patients receiving therapeutic anticoagulation

Yosuf W. Subat,Hamza Rayes,Andrew C. Hanson,Madeline Q. Johnson,Phillip J. Schulte,Kimberly Evans,Timothy Weister,Vrinda Trivedi,Ognjen Gajic,Matthew A. Warner

Journal of Critical Care（2020）

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摘要

•Retrospective cohort study of ICU patients at Mayo Clinic Rochester from 2007 to 2016•Major bleeding occurred in 19% in aspirin alone, 22% in aspirin plus anticoagulation•Aspirin plus anticoagulation was not associated with increased risk of bleeding•Discontinuation of aspirin did not lead to increased stroke or myocardial infarction

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therapeutic anticoagulation,aspirin use,major bleeding,ill patients,non-surgical

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