Graphene-based electrochemical genosensor incorporated loop-mediated isothermal amplification for rapid on-site detection of Mycobacterium tuberculosis.

Wansadaj Jaroenram,Jantana Kampeera,Narong Arunrut,Chanpen Karuwan,Assawapong Sappat,Pakapreud Khumwan,Sarinya Jaitrong,Kobporn Boonnak,Therdsak Prammananan,Angkana Chaiprasert,Adisorn Tuantranont,Wansika Kiatpathomchai

Journal of Pharmaceutical and Biomedical Analysis（2020）

引用 27|浏览113

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摘要

•A novel integrated point-of-care system to detect Mycobacterium tuberculosis (MTB).•Consisting of LAMP and screen-printed graphene electrode for an electrochemical analysis.•The system showed high sensitivity and specificity when using a portable potentiostat.•It could determine the presence of MTB in 104 blinded samples with 100% accuracy.

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关键词

Mycobacterium tuberculosis,Mini-potentiostat,Graphene,Screen-printed electrode,LAMP-EC

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