Type 2 Inflammation Modulates ACE2 and TMPRSS2 in Airway Epithelial Cells.

Hiroki Kimura,Dave Francisco,Michelle Conway,Fernando D Martinez,Donata Vercelli,Francesca Polverino,Dean Billheimer,Monica Kraft

Journal of Allergy and Clinical Immunology（2020）

引用 294|浏览30

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摘要

IL-13 modulates ACE2 and TMPRSS2 expression in airway epithelial cells in asthma. This deserves further study with regard to any effects asthma and atopy may render in the setting of COVID-19 infection.

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关键词

Asthma,IL-13,ACE2,TMPRSS2,nasal epithelial cells,airway epithelial cells,COVID-19,SARS-CoV-2,type 2 inflammation

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