A Polymeric Solid-Phase Microextraction Fiber for the Detection of Pharmaceuticals in Water Samples
Journal of chromatography A/Journal of chromatography(2020)
Abstract
A novel disposable styrene based solid-phase microextraction (SPME) fiber was synthesized for the detection of lipid-lowering and antihypertensive drugs in real aquatic environment. Styrene and poly(ethylene glycol) diacrylate were co-polymerized on quartz fibers by thermal polymerization in capillary molds. The polymeric fiber possessed a homogeneous, dense as well as porous surface, showing excellent chemical and mechanical stability. The performance of the fiber was evaluated through the extraction of seven pharmaceuticals by coupling SPME with high performance liquid chromatography-tandem mass spectrometry under the optimized extraction conditions. The extraction efficiency of the fiber was up to 278 times of PDMS fiber and the enrichment factors ranged from 55 to 1183. The limits of detection were in the range from 1.7 ng L-1 to 11.7 ng L-1, with good reproducibility. Moreover, the fiber was used in the real water samples of the Pearl River Delta. The recoveries of the target analytes from river water and sea water samples at different spiked concentrations were in the range from 84.1% to 133.4% and from 81.5% to 105.5%, respectively. (C) 2020 Elsevier B.V. All rights reserved.
MoreTranslated text
Key words
Solid-phase microextraction,Polymeric fiber,High performance liquid chromatography-tandem mass spectrometry,Lipid-lowering and antihypertensive drugs
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined