Transcriptomic Identification of TMIGD1 and Its Relationship with the Ileal Epithelial Cell Differentiation in Crohn’s Disease

This is a single-center translational research study that aimed to look for key targets involved in Crohn’s disease and define molecular pathways through different functional analysis strategies. With this approach, we have identified and described a novel target, the almost unknown TMIGD1 gene, which may be key in the recovery of injured mucosa involving intestinal epithelial cell differentiation.