Computational Model Reveals a Stochastic Mechanism behind Germinal Center Clonal Bursts
CELLS, pp. 14482020.
Germinal centers (GCs) are specialized compartments within the secondary lymphoid organs where B cells proliferate, differentiate, and mutate their antibody genes in response to the presence of foreign antigens. Through the GC lifespan, interclonal competition between B cells leads to increased affinity of the B cell receptors for antigen...More
Get fulltext within 24h
Full Text (Upload PDF)
PPT (Upload PPT)