18F-FDG Uptake in a Mesonephric Carcinoma.

We present the case of a 39-year-old woman with vaginal bleeding and abdominal pain. An F-18-FDG PET/CT showed high F-18-FDG uptake in a tumor in the pouch of Douglas, in 3 lymph nodes in the pelvis, and in the left tuber ischiadicum. Biopsies revealed a mesonephric carcinoma with metastases. Six series of empiric chemotherapy with carboplatin, paclitaxel, and bevacizumab were not sufficient to treat the cancer, and checkpoint immunotherapy with nivolumab and ipilimumab was initialized.