Sex-specific differences in transcriptomic profiles and cellular characteristics of oligodendrocyte precursor cells

Ken Yasuda,Takakuni Maki,Ryusei Nishigori,Yusuke Kinoshita,Yuichi Ono,Ryosuke Takahashi

Stem Cell Research（2021）

引用 23|浏览7

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摘要

•There is substantial sexual dimorphism in functions and transcriptomes of OPCs.•Female OPCs have a higher capacity for proliferation and migration.•Male OPCs have a higher capacity for differentiation and myelination.•Female OPCs are more resistant to oxygen-glucose deprivation.

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关键词

Oligodendrocyte precursor cells,Oligodendrocytes,Blood–brain barrier,Sex differences

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