Is increased symptom interval associated with advanced stage and poorer outcome? A prospective multicenter study of 220 patients with osteosarcoma around the knee.

Jianping Hu,Chunlin Zhang,Kunpeng Zhu,Lei Zhang,Tao Cai,Taicheng Zhan,Xiong Luo,Yang Dong

Cancer Epidemiology（2020）

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摘要

•Interquartile range is a better method than setting a cut-off point.•Patients with the shortest symptom have better prognosis.•Timely referral and quick initial diagnosis are still the recommendation.

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关键词

Osteosarcoma,Symptom interval,Overall survival,Metastases,Prognostic factor,Kaplan-meier analysis

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