Antibacterial Activity and DNA Interaction of the Pd ( bpy ) ( ONO 2 ) 2 Coordination Complex

Antibacterial activity of Pd(bpy)(ONO2)2 complex (bpy = bipyridine) was studied by disc diffusion method against Escherichia coli, Staphylococcus aureus, Klebsiella oxytoca, Pseudomonas aeruginosa and Enterococcus faecalis. The compound was found to be active against the bacteria. DNA binding constant of that complex was studied with extracted DNA from lemon by UV-Vis spectroscopy. The calculated binding strength was found to be 2.09×10 6 which is significantly higher than that of the [Pd(bpy)(OH2)2] 2+ complex with CT-DNA.