Cannabinoid type 1 receptor blockade promotes mitochondrial biogenesis through eNOS expression in white adipocytes

Integrated Laboratories Network, Center for Study and Research on Obesity, Department of Pharmacology, Chemotherapy and Medical Toxicology, School of Medicine, Milan University, Milan, Italy; Istituto Auxologico Italiano, Milan, Italy; Department of Biomedical Sciences and Biotechnologies, Brescia University, Brescia, Italy; Endocrinology Unit, Department of Internal Medicine and Gastroenterology, and Center for Applied Biomedical Research S. OrsolaMalpighi Hospital, Alma Mater Bologna University, Bologna, Italy; Endocrine-Metabolic Laboratory, Internal Medicine, Department of Medical and Surgical Sciences, Padua University, Padua, Italy; U862 INSERM, Group AVENIR, Institute François Magendie, University Bordeaux 2, Bordeaux, France; Department of Physiological Chemistry, Johannes Gutenberg University Mainz, Mainz, Germany.