Pericytes and immune cells contribute to complement activation in 1 tubulointerstitial fibrosis 2 3

Pericytes and immune cells contribute to complement activation in 1 tubulointerstitial fibrosis 2 3 Sandhya Xavier, Ranjit K Sahu, Susan G Landes, Jing Yu , Ronald P Taylor, Srinivas Ayyadevara, Judit 4 Megyesi, William B Stallcup, Jeremy S Duffield, Edimara S Reis, John D Lambris, Didier Portilla. 5 6 7 Division of Nephrology, Center for Immunity, Inflammation and Regenerative Medicine, Department of 8 Cell Biology, Department of Biochemistry, University of Virginia, Charlottesville, Virginia, University of 9 Arkansas for Medical Sciences, Little Rock, Arkansas, Sanford Burnham Prebys Medical Discovery 10 Institute, Tumor Metastasis and Cancer Immunology Program, La Jolla, California, Research and 11 Development, Biogen Idec, Cambridge, Massachusetts Department of Pathology and Laboratory 12 Medicine University of Pennsylvania, Philadelphia, Pennsylvania Salem Veterans Affairs Medical 13 Center, Salem, Virginia 14 15 16 17 18 Running title: Pericytes, Complement and kidney fibrosis 19