Cortical gray matter variations in young women at high risk for familial depression and their depressed mothers with ( positive ) family history

CARS score was significantly correlated with the severity of ASD diagnosis according to DSM-5 (p=0.027). However, ABC score was not correlated with the severity of ASD diagnosis according to DSM-5 (p=0.370). Comorbid psychiatric disorders according to K-SADS in the ASD-diagnosed group were found as ADHD in 6 children, depression in 1 child, conduct disorder in 1 child, enuresis in 2 children, encopresis in 1 child, and tic disorder in 1 child. Only in 1 child, ADHD was found as a comorbidity in the undiagnosed group. CONCLUSION: In spite of the limited sample size of our study, it was observed that 64.3% of patients met criteria for ASD based on DSM-5 at re-evaluation after 4 years from the first diagnosis. None of the cases which were not diagnosed as ASD met the criteria of Social Communication Disorder, which is a new diagnosis in DSM-5; however, this result might be related to the limited size of our sample. Psychiatric disorders were found more common in the ASD-diagnosed group. In this study, we observed that there was a statistically significant correlation between ASD diagnosis based on DSM-5 and CARS and ABC scores. The results of our study and the present literature were found to be consistent. We consider that it would be convenient to support these findings with other studies in Turkey with an increasing sample size.