P4-084 genome-wide association study using cerebrospinal fluid biomarkers beta- amyloid-42 and ptau181 in german samples ofalzheimer’s disease

CEREBROSPINAL FLUID BIOMARKERS BETAAMYLOID-42 AND PTAU181 IN GERMAN SAMPLES OFALZHEIMER’S DISEASE Alfredo Ramirez, Christine Herold, Piotr Lewczuk, Andr e Lacour, Dmitriy Drichel, Britta Sch€urmann, Johannes Kornhuber, Oliver Peters, Reiner Heun, Harald Hampel, Lutz Fr€olich, Michael H€ull, Per Hoffmann, Stefani Vogt, Heike K€olsch, Michael Heneka, Judith Alferink, Eckart R€uther, Jens Wiltfang, Martin Dichgans, Max Baur, Frank Jessen, Wolfgang Maier, Tim Becker, Markus N€othen, University of Bonn, Bonn, Germany; DZNE, Bonn, Germany; University of Erlangen-N€urnberg, Erlangen, Germany; Charit e, Berlin, Germany; Department of Psychiatry, Royal Derby Hospital, Derby, United Kingdom; 6 University of Frankfurt, Frankfurt am Main, Germany; 7 Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany; University of Freiburg ZGGF, Freiburg, Germany; University of G€ottingen, G€ottingen, Germany; University of Duisburg-Essen, Essen, Germany; 11 University of Munich, Munich, Germany; 12 University of Bonn, Department of Psychiatry, Bonn, Germany.