Synthesis , characterization and antimicrobial activity of novel quaternized poly ( styrene ethylene butylene poly styrene )

semanticscholar(2010)

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摘要
A new class of biologically potent compound was derived from poly (styrene ethylene butylene poly styrene) via. Chloromethylation and Quaternization. Quaternized poly (styrene ethylene butylene poly styrene) [QPSEBS] is a type of anion exchange polymer. The functionalized polymer was characterized by FT-IR and H-NMR spectroscopy. The present investigation is centered on the antimicrobial activity of the QPSEBS polymer. The QPSEBS polymer was found to show antibacterial activity towards the Gram-positive bacteriae (Bacillus subtilis, Staphyloccus aureus and Pseudomonas aeruginosa) and Gram-negative bacteria (Escherichia coli, Klebsiella pneumonia) which was determined by agar diffusion method used with tetra cycline as a reference control. The minimum inhibitory concentration (MIC) was observed against all the five pathogenic bacteriae.
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