Comparative Medication Histories Between Newly Hospitalized Hypertensive Patients and Hypertensive Outpatients in Cote D ’ Ivoire Danho

Introduction: The aim of medication history is to specify behaviors that can influence treatment and it is part of an aid to educational diagnosis and medication reconciliation. The objective of our study was to identify factors that may contribute to hospitalization, poor therapeutic response or the occurrence of drugs adverse events in newly hospitalized hypertensive patients (NHP) and hypertensive outpatients (HOP). Methods: A comparative descriptive cross-sectional study was carried out from January 2014 to June 2015 in hospitalization units (department of internal medicine at teaching hospital of Treichville and department of neurology at teaching hospital of Cocody) and ambulatory follow-up unit (medical consultation department at Heart Institute of Abidjan) with hypertensive patients in Cote d’Ivoire. A semi-directive interview was conducted with a questionnaire of medication history with the following factors: factors related to the understanding of treatment (FUT), factors related to the monitoring of the treatment (FMT), factors related to dietetichygienic measures (FDHM), factors related to the effects of treatment (FET), factors related to patients (FP). Results: A total of 50 NHP and 100 HOP were recruited. For FMT, regular monitoring by a physician [NHP (52%) vs HOP (64%); p= 0.00006)], occasional discontinuation of medication [NHP (54%) vs HOP (27%); p = 0.001], satisfaction with the mode and forms of drug administration [NHP (72%) vs HOP (88%); p = 0.014], monitoring by several doctors [NHP (24%) vs HOP (0%); p = 0.001] and the frequency of biological assessments [NHP (34%) vs HOP (87%); p= 0.001] differed significantly between both groups. Among factors related to hygienic-dietetic measures, only the presence of stress and anxiety differed significantly [NHP (88%) vs HOP (72%), p = 0.02]. For factors related to the effects of treatment, the perception of adverse drug effects greater than beneficial effects differed significantly [NHP (2%) vs HOP (11%); p = 0.047]. Allergy to certain drugs [NHP (12%) vs HOP (33%); p = 0.0057] is a factor related to patients that differed significantly between both groups. However, most of FUT, FP, FET and FDHM differed in a non-significant way between NHP and HOP. Conclusion: Factors related to NHP are elements to be considered in an educational program of HOP or on leaving hospital.