Structural insight into selectivity and resistance profiles of ROS 1 tyrosine kinase inhibitors

Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239; Department of Pediatrics, Oregon Health & Science University, Portland, OR 97239; Huntsman Cancer Institute, The University of Utah, Salt Lake City, UT 84112; Division of Hematology and Hematologic Malignancies, The University of Utah, Salt Lake City, UT 84112; Division of Hematology and Medical Oncology, Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239; Howard Hughes Medical Institute, Portland, OR 97239; and Memorial Sloan Kettering Cancer Center, New York, NY 10065