Successful therapy of murine visceral leishmaniasis with a strakurkurone , a triterpene 1 isolated from mushroom

Successful therapy of murine visceral leishmaniasis with astrakurkurone, a triterpene 1 isolated from mushroom Astraeus hygrometricus, involves the induction of protective 2 cell mediated immunity and TLR9. 3 4 Suvadip Mallick, Aritri Dutta, Ankur Chaudhuri, Debasri Mukherjee, Somaditya Dey, 5 Subhadra Halder, Joydip Ghosh, Debarati Mukherjee, Sirin Salma Sultana, Gunjan 6 Biswas, Tapan Kumar Lai, Pradyumna Patra, Indranil Sarkar, Sibani Chakraborty, 7 Bhaskar Saha, Krishnendu Acharya and Chiranjib Pal* 8 9 Cellular Immunology and Experimental Therapeutics Laboratory, Department of Zoology, 10 West Bengal State University, Barasat, West Bengal, India 11