Formulation and in-vitro dissolution of Clopidogrel tablet by using sodium starch glycolate and natural xanthan gum

Different formulations were made with an aim to develop stable, cost effective Clopidogrel tablets by direct compression technique. Four formulations (F1 – F4) having Primojel and xanthan gum at different concentrations level were prepared. The prepared batches of tablets were evaluated for hardness, friability, disintegration and in-vitro dissolution study. All The formulations containing combination of Primojel and Xanthan gum showed different in-vitro disintegration time and drug release.