The BEACH-domain containing protein, Nbeal2, interacts with Dock7, Sec16a and Vac14 Running head: Biochemical interactions of Nbeal2

Louisa Mayer, Maria Jasztal, Mercedes Pardo, Salvadora Aguera de Haro, Janine Collins, Tadbir K Bariana, Peter A Smethurst, Luigi Grassi, Romina Petersen, Paquita Nurden, Rémi Favier, Lu Yu, Stuart Meacham, William J Astle, Jyoti Choudhary, Wyatt W Yue, Willem H Ouwehand, Jose A Guerrero Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK. National Health Service Blood and Transplant, Cambridge Biomedical Campus, Cambridge, UK. Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK. 4 Department of Haematology, Barts Health National Health Service Trust, London, UK. Katharine Dormandy Haemophilia Centre and Thrombosis Unit, Royal Free London NHS Foundation Trust, London, UK. Department of Haematology, University College London Cancer Institute, London, UK. Institut Hospitalo-Universitaire L’Institut de Rythmologie et Modelisation Cardiaque, Hopital Xavier Arnozan, Pessac, France. Département d’Hématologie, Assistance-Publique Hôpitaux de Paris, Centre de Référence des Pathologies Plaquettaires, Hôpital Armand Trousseau, Paris, France. Institut National de la Santé et de la Recherche Médicale U1170, Villejuif, France. MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Wort’s Causeway, Cambridge, UK. Structural Genomics Consortium, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK. Blood First Edition Paper, prepublished online November 29, 2017; DOI 10.1182/blood-2017-08-800359