The continuing challenge of understanding and preventing neural tube defects

John B. Wallingford1,*, Lee A. Niswander2, Gary M. Shaw3, and Richard H. Finnell4 1Howard Hughes Medical Institute, Department of Cellular, Molecular and Developmental Biology, The University of Texas at Austin, Austin, Texas 2Howard Hughes Medical Institute, Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado 3Department of Pediatrics, Stanford University School of Medicine, Stanford, California 4Dell Pediatric Research Institute, Departments of Nutritional Sciences, Chemistry and Biochemistry, The University of Texas at Austin, Austin, Texas