Therapeutic enhancement of blood-brain and blood-tumor barriers permeability by laser interstitial thermal therapy.

Afshin Salehi, Mounica R Paturu,Bhuvic Patel,Matthew D Cain,Tatenda Mahlokozera,Alicia B Yang,Tsen-Hsuan Lin,Eric C Leuthardt,Hiroko Yano,Sheng-Kwei Song,Robyn S Klein,Robert Schmidt,Albert H Kim

Neuro-oncology advances（2020）

引用 29|浏览20

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摘要

Together, these results suggest that LITT can locally disrupt the BBB and BTB, enabling the targeted delivery of systemic therapies, including, potentially, antibody-based agents.

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关键词

blood–brain barrier,blood–tumor barrier,central nervous system tumors,glioblastoma,laser interstitial thermal therapy

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