H3K9me3-mediated epigenetic regulation of senescence in mice predicts outcome of lymphoma patients.

Kolja Schleich
Kolja Schleich
Julia Kase
Julia Kase
Saskia Trescher
Saskia Trescher
Animesh Bhattacharya
Animesh Bhattacharya
Elizabeth M Wailes
Elizabeth M Wailes
Dorothy N Y Fan
Dorothy N Y Fan
Andrea Lau
Andrea Lau

NATURE COMMUNICATIONS, pp. 3651-3651, 2020.

被引用0|浏览8
WOS

摘要

Lesion-based targeting strategies underlie cancer precision medicine. However, biological principles - such as cellular senescence - remain difficult to implement in molecularly informed treatment decisions. Functional analyses in syngeneic mouse models and cross-species validation in patient datasets might uncover clinically relevant gen...更多

代码

数据

ZH
24小时获取PDF
引用
您的评分 :
0

 

标签
评论