H3K9me3-mediated epigenetic regulation of senescence in mice predicts outcome of lymphoma patients.
NATURE COMMUNICATIONS, pp. 3651-3651, 2020.
Lesion-based targeting strategies underlie cancer precision medicine. However, biological principles - such as cellular senescence - remain difficult to implement in molecularly informed treatment decisions. Functional analyses in syngeneic mouse models and cross-species validation in patient datasets might uncover clinically relevant gen...更多
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