Monoclonal Antibody Against ROR1 Induces Apoptosis in Human Bladder Carcinoma Cells.

Ali-Ahmad Bayat,Niloufar Sadeghi,Ramina Fatemi,Mohammad Reza Nowroozi,Solmaz Ohadian Moghadam, Mohadeseh Borzuee,Amin Radmanesh,Mahmood Khodadoost,Ali Reza Sarrafzadeh,Omid Zarei,Hodjattallah Rabbani

Avicenna journal of medical biotechnology（2020）

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摘要

Taken together, our finding indicates the role of ROR1 in bladder cancer cell survival and suggests this receptor might be a promising target for developing novel therapeutic agents against bladder carcinoma.

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关键词

Bladder cancer,Flow cytometry,Monoclonal antibody,ROR1 protein

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