Plerixafor stimulates adhesive activity and endothelial regeneration of endothelial progenitor cells via elevating CXCR7 expression

•CXCR7 is expressed by EPCs.•SDF-1/CXCR7 axis regulated adhesive capacity of EPCs.•Plerixafor stimulate EPCs adhesive activity via elevating CXCR7 expression and activating LFA-1 and VLA-4 molecules.•Plerixafor accelerated re-endothelialization and inhibited neointimal hyperplasia via recruiting more EPCs.