High Contrast Probe Cleavage Detection

Michael Dubrovsky,Morgan Blevins,Svetlana V. Boriskina,Diedrik Vermeulen

Frontiers in Optics（2020）

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摘要

We will discuss a new sensing modality, High Contrast Probe Cleavage Detection (HCPCD), for photonic biosensors that can be combined with recent developments in biochemistry, such as CRISPR Cas12/13 assays, to deliver highly sensitive and specific RNA and DNA detection.

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