Cd98hc: A Novel Treatment Target In Malignant Mesothelioma

Claire Rooney,Lynda Vuong,Tariq Sethi,Alison Mackinnon,Frank McCaughan

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE（2017）

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摘要

Aims:1) Develop and functionally characterise a series of cell lines with the capacity to inducibly knockdown CD98 2) Test the impact of genetic or therapeutic targeting of CD98 using human xenograft and syngeneic murine models of MM in vivoMethods:

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