TET2 promotes IL-1β expression in J774.1 cell through TLR4/MAPK signaling pathway with demethylation of TAB2 promoter

Yu Liang,Jingyuan Zeng,Bo Luo,Wei Li,Yancheng He,Wenjing Zhao,Nan Hu,Nan Jiang,Yujiao Luo,Yujun Xian,Jiajia Liu,Xiaoli Zheng

Molecular Immunology（2020）

引用 3|浏览17

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摘要

•TET2 can promote the expression of IL-1β through TLR4/MAPK signaling pathway in J774.1.•TET2 is involved in TLR4 signaling pathway regulation by changing methylation levels of TAB2 promoter in J774.1.

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关键词

TET2,Macrophage,IL-1β,5mC

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