Posaconazole and fluconazole prophylaxis during induction therapy for pediatric acute lymphoblastic leukemia

Tian Zhang, Jie Bai, Mingxia Huang,Ruixiao Li,Yang Liu,Ansheng Liu,Jixin Liu

Journal of Microbiology, Immunology and Infection（2021）

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摘要

Our findings supported using targeted prophylaxis with posaconazole in ALL children undergoing induction chemotherapy. Age, clinically documented bacterial infection and ANC are important predictors of invasive fungal infections in patients with posaconazole prophylaxis.

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关键词

Prophylaxis,Child,Acute lymphoblastic leukemia,Invasive fungal infection

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