An Acridine-Based Fluorescent Sensor For Monitoring Clo(-)In Water Samples And Zebrafish

A novel acridine-based fluorescent chemosensor,BK((E)-2-((acridine-9-ylimino)methyl)-N-benzhydrylhydrazine-1-carbothioamide), for monitoring ClO(-)was prepared. The sensorBKwas synthesized by introducing a new synthetic route of making aldehyde group using formic hydrazide. ProbeBKdisplayed notable fluorescence quenching in the presence of ClO(-)and showed a great selectivity over other guest analytes. The detection limit was calculated to be 7.65 mu M. Additionally,BKwas satisfactorily applied for sensing ClO(-)in water samples and zebrafish.