Detection of Structural Rearrangements in Embryos

Svetlana Madjunkova,Yogi Sundaravadanam,Ran Antes,Rina Abramov,Siwei Chen,Yin Yin,Philip C Zuzarte,Sergey I Moskovtsev,Lars G T Jorgensen,Ari Baratz,Jared T Simpson,Clifford Librach

NEW ENGLAND JOURNAL OF MEDICINE（2020）

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摘要

Balanced Translocations in Embryos Balanced chromosomal rearrangements are associated with infertility and recurrent miscarriage but are difficult to detect. In this study, long-read DNA sequencing...

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