Switch maintenance chemotherapy versus observation after carboplatin and weekly paclitaxel doublet chemotherapy in elderly patients with advanced non–small cell lung cancer: IFCT-1201 MODEL trial

European Journal of Cancer(2020)

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摘要
•Chemotherapy remains a backbone in lung cancer treatment.•Maintenance chemotherapy has proven beneficial in non–small cell lung carcinoma with metastatic stage.•There is a selection bias for older patients included in non-dedicated studies.•This trial shows that elderly do not derive any survival benefit with maintenance.•It illustrates that dedicated studies for elderly patients are mandatory.
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关键词
NSCLC,Elderly,Chemotherapy,Maintenance
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