Long Sleep Duration and Risk of Increased Arterial Stiffness in a Chinese Population

Abstract To examine the relationship between self-reported sleep duration and arterial stiffness in a large Chinese population from Kailuan. From July 2010 to December 2015, a total of 17,018 participants aged 18 to 98 years were enrolled after excluding those with a history of cerebrovascular events and coronary artery disease. Participants were divided into 5 categories according to self-reported night sleep duration: ≤5.0, 6.0, 7 (ref), 8, and ≥9.0 hours. A brachial-ankle pulse wave velocity ≥1400 cm/s was considered to represent arterial stiffness. Multivariate logistic regression models were used to calculate the odds ratio (OR) and confidence interval (CI) for arterial stiffness according to the sleep duration. Using 7 hours of sleep as the reference group, the multivariable adjusted ORs (95% CI) for arterial stiffness were 1.00 (0.87–1.16), 1.00 (0.90–1.11), 1.0 (ref), 1.03 (0.93–1.14), and 1.48 (1.05–2.08) from the lowest to highest category of sleep duration, respectively. Secondary analysis showed no evidence of interactions between sleep duration and age/sex on the risk of arterial stiffness (P-interaction = .390/.198). A long night sleep duration was associated with increased arterial stiffness.