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The Model of Degradable Polymer PLGA Deformed by Hot Embossing Method

PROCEEDINGS OF THE 2015 2ND INTERNATIONAL WORKSHOP ON MATERIALS ENGINEERING AND COMPUTER SCIENCES (IWMECS 2015)(2015)

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摘要
A novel drug delivery microsystem is proposed in this paper, which consists of the microstructure for drug loading and the bonding membrane with microholes for release rate controlling. The forming process of microstructure by hot embossing method was researched. For the microstructure was fabricated by degradable polymer which possess the viscoelastic property, the numerical material model was established based on the generalized Maxwell model with 5 units, and the relaxation parameters in this model were confirmed by the stress relaxation experiment. The simulation results show that the model is reasonable and give the base for the optimum parameters research by hot embossing.
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关键词
Degradable polymer,hot embossing,simulation model,controlled drug delivery
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