THE CORRELATION BE'T'WEEN QUALITY OF LIFE AND NEGATIVE EMOTION IN ADMIT'T'ED PATIENTS WITH NASOPHARYNGEAL CARCINOMA AT DIFFERENT STAGES

Objective: This study aims to investigate the occurrence of negative emotion and quality of We in patients with newly diagnosed nasopharyngeal carcinoma (NPC), and analyze its correlation. Methods: The quality of life of 75 NPC patients was investigated at the time of admission, during the treatment and at the end of treatment using the Quality of Life Questionnaire Core 30 (QLQ-C30), Zung self-rating depression scale (SDS) and self rating anxiety scale (SAS). Results: At the time of admission, the middle point of treatment and at the end of treatment, the SAS score was 41.78 +/- 826, 45.19 +/- 9.44 and 47.92 +/- 10.59, respectively; and the SDS score was 51.55 +/- 8.82, 52 35 +/- 8.74 and 5427 +/- 9.06, respectively. The incidence of anxiety was highest the middle point of treatment (P<0.05). At the end of treatment, the differences in physical, emotional and cognitive functions, fatigue, pain, insomnia and constipation symptoms at the time of admission and the middle point of treatment were statistically significant (P<0.05). Anxiety and depression were negatively correlated with the functional area and overall health status but were positively correlated with symptoms (P<0.05). Conclusion: The occurrence of negative emotion at different stages of hospitalization in patients with newly diagnosed NPC varies, and quality of life is affected at different degrees. Corresponding psychological nursing should be conducted for patients at different stages, in order to reduce the adverse effects of negative emotion on the mental health of patients and improve its rehabilitation effect.