Excitability of motor and sensory axons in multifocal motor neuropathy

Maria O. Kovalchuk,Hessel Franssen,Leonard H. van den Berg,Leonard J. van Schelven,Boudewijn T.H.M. Sleutjes

Clinical Neurophysiology（2020）

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摘要

•Excitability properties differ between motor and sensory axons in multifocal motor neuropathy (MMN).•Modeling suggests Barrett-Barrett and fast potassium conductances are increased in MMN.•Conductance changes indicate peripheral myelin sheath and paranodal seal involvement in MMN.

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关键词

Multifocal motor neuropathy,Excitability,Sensory axons,Motor axons,Ion channels,Schwann cell

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