ARPP19 promotes MYC expression and associates with patient relapse in acute myeloid leukemia

Eleonora Mäkelä,Eliisa Löyttyniemi,Urpu Salmenniemi,Otto Kauko,Taru Varila,Veli Kairisto,Maija Itälä-Remes,Jukka Westermarck

biorxiv（2019）

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摘要

Together, these data identify ARPP19 as a novel oncogenic PP2A inhibitor protein in AML, and demonstrate its risk group independent role in predicting AML patient relapse tendency.

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关键词

Cancer,ARPP-19,PME-1,SET,WT1

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