Platelet counts predict prognosis in IPF, but are not the main source of pulmonary TGFβ1
biorxiv(2020)
摘要
Our results demonstrate for the first-time that platelet-derived TGFβ1 is redundant in driving pulmonary fibrosis in an animal model. However, platelets can predict mortality in IPF implicating other platelet-derived mediators, such as CCL5, in promoting human IPF disease.
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关键词
platelet,prognosis
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