Intelligent cell-based therapies for cancer and autoimmune disorders

Rui Chen,Ji Jing,Stefan Siwko,Yun Huang,Yubin Zhou

Current Opinion in Biotechnology（2020）

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摘要

•Emerging strategies to develop smart and controllable CAR T-cells.•Devising CAR T-cells to overcome immunosuppressive tumor microenvironment.•CAR engineering in natural killer cells and macrophages to expand immunotherapy.•Engineered immune cells used to target autoimmune disorders.

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