Sensitive Detection Of Sars-Cov-2-Specific Antibodies In Dried Blood Spot Samples

Gabriella L Morley,Stephen Taylor,Sian Jossi,Marisol Perez-Toledo,Sian E Faustini,Edith Marcial-Juarez,Adrian M Shields,Margaret Goodall,Joel D Allen,Yasunori Watanabe,Maddy L Newby,Max Crispin,Mark T Drayson,Adam F Cunningham,Alex G Richter,Matthew K O'Shea

EMERGING INFECTIOUS DISEASES（2020）

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摘要

Dried blood spot (DBS) samples can be used for the detection of severe acute respiratory syndrome corona virus 2 spike antibodies. DBS sampling is comparable to matched serum samples with a relative 98.1% sensitivity and 100% specificity. Thus, DBS sampling offers an alternative for population-wide serologic testing ill the coronavirus pandemic.

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关键词

COVID-19,DBS,SARS-CoV-2,antibody,coronavirus disease,dried blood spot,respiratory infections,severe acute respiratory syndrome coronavirus 2,viruses,zoonoses

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