Evaluation Of Two Point Of Care Technologies For Measuring Monoclonal Antibody Therapeutic-A Concentrations In Blood

BIOANALYSIS(2020)

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摘要
Aim:Current blood monitoring methods require sample collection and testing at a central lab, which can take days. Point of care (POC) devices with quick turnaround time can provide an alternative with faster results, allowing for real-time data leading to better treatment decisions for patients.Results/Methodology:An assay to measure monoclonal antibody therapeutic-A was developed on two POC devices. Data generated using 75 serum samples (65 clinical & ten spiked samples) show correlative results to the data generated using Gyrolab technology.Conclusion:This case study uses a monoclonal antibody therapeutic-A concentration assay as an example to demonstrate the potential of POC technologies as a viable alternative to central lab testing with quick results allowing for real-time decision-making.
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关键词
anti-A, Gyrolab, monoclonal antibody therapeutic A, POC, point of care, proxim, qorvo, TDM, therapeutic drug monitoring
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