Asthma in farm children is more determined by genetic polymorphisms and in non-farm children by environmental factors.

Norbert Krautenbacher,Michael Kabesch,Elisabeth Horak,Charlotte Braun-Fahrländer,Jon Genuneit,Andrzej Boznanski,Erika von Mutius,Fabian Theis,Christiane Fuchs,Markus J Ege

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology（2020）

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摘要

Asthma in farm children is more likely predicted by other factors as compared to non-farm children though in both forms, family history may integrate environmental exposure, genotype, and degree of penetrance.

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关键词

Childhood asthma,GWAS,SNPs,environment,farming,machine learning,penalized regression,random forest,risk prediction,statistical learning

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