Extent and prevalence of post-exercise and nocturnal hypoglycemia following peri-exercise bolus insulin adjustments in individuals with type 1 diabetes

•Exercise-related hypoglycemia continues to represent a major clinical concern in the glycemic management of people with T1D.•Though the integration of bolus insulin dose reductions around physical exercise is recognised as an integral component of an optimal glycemic management plan in people with T1D, less work has systemically investigated the extent and prevalence of venous blood confirmed hypoglycemia following specific peri-exercise bolus dose adjustments made on a background of ultra-long acting insulin degludec.•Using current generation insulin analogues, the results of this study provide up to date reaffirmation of the glycemic safety of integrating bolus insulin dose reductions around dynamic physical exercise in people with T1D treated with novel, ultra-long acting basal insulins.