3D engineering for optic neuropathy treatment

Wenjing Xuan, Aji Alex Moothedathu,Tuo Meng, David C. Gibson,Jinhua Zheng,Qingguo Xu

Drug Discovery Today（2021）

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摘要

•3D engineering for recapitulating ocular pathophysiology and retina development.•The development of retina and its 3D model engineering for optic neuropathies.•The application of pluripotent stem cells in disease modelling, drug screening, and cell and gene therapies.•The perspectives of 3D models in new therapy development for optic neuropathies.

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