Paternal cannabis extract exposure in rats: Preconception timing effects on neurodevelopmental behavior in offspring

•Neurobehavioral effects of rat paternal cannabis exposure was assessed in their offspring.•On the elevated plus maze, offspring of cannabis exposed males had greater risk-taking.•In novel object recognition, male offspring of cannabis-exposed males had a greater drop-off in novelty preference.•In the 16-arm maze. female offspring cannabis-exposed males had more working memory errors in early training.•There are long-lasting behavioral consequences of preconception paternal cannabis exposure in rats.