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Evaluation of the clinical course and prognostic indices of acute pancreatitis in elderly patients : a prospective study

H. Satis, N. Kayahan,Z. G. Sargin,A. Karatas, D. Celiker

ACTA GASTRO-ENTEROLOGICA BELGICA(2020)

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摘要
Background and aim : Acute pancreatitis (AP) is a life-threatening condition across all age groups. In this study, it was aimed to investigate the severity of the disease and associated mortality in the geriatric population. Methodology : This single-center; prospective study elderly (>= 65 years of age) and younger (18-65 years of age) total 147 patients with AP are enrolled To diagnose and asses the severity of AP Atlanta classification was used. Baseline and 12-months follow-up data included Ranson, Imrie, BISAP,APACHE-II, SOFA, Modified Marshall, Balthazar, and Computed Tomography Severity Index (CTSI) as prognostic tools. Results : 6 (15%) patiens in elderly and 5 (6,7%) patients in non elderly group had modarete-severe AP. Patients were followed up 1 year and during this time no systemic complications were seen , 8 (20%) patients in elderly group and 10(13,6%) patients in younger group had local complications. I patients in elderly and 2 patients in non elderly group had acute necrotic collection whereas 1 patient developed walled of necrosis in non elderly group. The elderly patients with any of the following index characteristics would not be expected to have a mild disease course: Imrie score 2. 3, BISAP score >= 3, APACHE-II >= 11, CRP >= 195 mg/dl Conclusions : AP caused a prolonged hospitalization in the elderly compared to younger patients but its severity and clinical outcomes were not different in the two groups.
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关键词
Acute pancreatitis,APACHE,Blood urea nitrogen,C-reactive protein,elderly patients,prognosis
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