Coding Complete Genome Sequences of Twenty three SARS CoV 2 Strains Isolated in the Philippines

medRxiv(2020)

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摘要
Here, we report the coding complete genome sequences of 23 severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) strains from the Philippines. Sequences were obtained from nasopharyngeal and oropharyngeal swabs from COVID-19 positive patients. Mutation analysis showed the presence of the D614G mutation in the spike protein in 22 of 23 genomes. ### Competing Interest Statement The authors have declared no competing interest. ### Funding Statement This study was funded by the Armed Forces Health Surveillance Branch (AFHSB) and its Global Emerging Infections Surveillance (GEIS) Section, USA under grant number P0128\_20\_AF_13 for FY 2020. ### Author Declarations I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. Yes The details of the IRB/oversight body that provided approval or exemption for the research described are given below: Informed consent for was obtained from the patients for SARS-CoV-2 testing. Sample collection was considered as a public health effort and did not require an Institutional Review Board approved human use protocol. Material has been reviewed by the Walter Reed Army Institute of Research. There is no objection to its presentation and/or publication. The opinions or assertions contained herein are the private views of the author, and are not to be construed as official, or as reflecting true views of the Department of the Army or the Department of Defense. The investigators have adhered to the policies for protection of human subjects as prescribed in AR 70 25. All necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived. Yes I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance). Yes I have followed all appropriate research reporting guidelines and uploaded the relevant EQUATOR Network research reporting checklist(s) and other pertinent material as supplementary files, if applicable. Yes The SARS-CoV-2 genomes from the Philippines were deposited in the GenBank database (accession nos. MT919768-90). The raw reads have been deposited in the NCBI Sequence Read Archive (SRA accession nos. SRS7273360-82). The Bio Project accession no. is PRJNA659293. The Bio Sample accession nos. are SAMN15903138-60.
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complete genome sequences,twenty-three,sars-cov
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